Signal constant (derived from T1 mapping series) the tissue magnetization calculated from the set of flip angle images, measured in AU Transfer constant from the blood plasma into the EES the relationship between VIF and contrast concentration, measured in 1 / minute Transfer constant from the EES back to the blood plasma, measured in 1 / minutes

Initial Slope (aka Wash-In) the rate of signal change from the beginning of contrast arrival to the time of maximal signal, measured in AU / s. Initial Area Under the Curve the area under the signal curve measure from the first time point of the perfusion scan to the specified time (30, 60 or 90 seconds), measured in AU x s Safetyīecause the IB DCE OsiriX Plugin is designed for the purpose of generating medical information, it raises some potential, though minor, safety concerns:Īrbitrary Units the units of the acquired MR signalĭigital Imaging and Communications in Medicine IB DCE is a component module of IB Clinic™, Imaging Biometrics' FDA-cleared and CE Marked post-processing toolkit. Automated vascular input function (VIF) generation.Ability to integrate with multiple PACS to access acquired data and to distribute results.Default settings that allow generation of parametric images with about three clicks.Selection of multiple DCE pharmacokinetic models, including Tofts, Extended Tofts, and Patlak.The plugin also includes such features as: These include the K trans transfer constant extra-vascular, extra-cellular fractions (v e) and blood plasma fraction (v p).

Using proprietary algorithms, it generates dynamic contrast enhancement (DCE) parametric images. The IB DCE OsiriX plugin performs post-processing of dynamically acquired MR datasets to evaluate image intensity variations over time.

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